Aruba, Netherlands Antilles. Since , when first described, colloid milium has been considered uncommon. In , Ferreira-Marques and van Uden 1 reviewed the literature and could ascertain only 60 recorded cases. In , Zoon, 2 who wrote authoritatively on the subject, referred to colloid milium as "rare. Significantly, Quin and Seale state that they "do not believe the condition is as rare as the sparsity of reports would indicate.
An otherwise healthy year-old white man presented for evaluation of a long-standing, progressive eruption on his cheeks. On physical examination, the affected areas showed large yellowish plaques composed of minute pseudovesicular lesions Figure 1. The patient admitted to a long history of unprotected sun exposure. His medical history was negative for photosensitizing medications and disorders, and there was no family history of similar skin findings. A biopsy specimen, which was obtained from a representative area on the left cheek, revealed deposition of eosinophilic hyalinized material within the papillary dermis. These large collections distended the dermal papillae, and the hyalinized material showed fracturing artifact. The results of Congo red staining were positive.
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Colloid milium is a rare cutaneous condition with at least three distinct subtypes, characterized clinically by the development of yellowish translucent papules or plaques on sun-exposed skin, and histologically by the presence of colloid in the dermal papillae. In this case report, we present a man with multiple small papules on dorsum of his hands that in pathology confirmed to be colloid milium. Colloid milium is more commonly observed in fair-skin patients and remain unchanged; however our patient had dark skin type Fitzpatrick skin type III and lesions were increasing in summer and decreasing in winter.